|Manufacturer||Heavy Industry Biocure|
|Common names||Genotropin, Humatrope, Norditropin, Jintropin, Somatropin, Somatotropin.|
Somatropin is recombiant injectable human growth hormone. It contents identical sequence of 191 amino acids of human growth hormone
The molecular formula is C990H1528 N262 O300 S7.lts molecular weight is 22,125 Daltons.
Joint and tendons strengthening
Improvement to skin appearance
New muscle cell formation
Increasing mineralization of bones
Increasing calcium retention
Accelerates wound healing
Androgenic index - None
Anabolic index - High
Aromatization - None
Acne - None
Toxicity for the liver – None
Water Retention - Rare
High Blood Pressure - Rare
Common cycle length is 3-6 months
Beginners: 4 - 5 iu / daily
Hobby: 5 – 10 iu / daily
Professional Range: 8 – 32 iu / daily
Women: 1 – 6 iu daily
Half-life: around 2,5 hours (active-life around 24 hours) note: active-life can be changed by injection method
Leukemia has occuired in a small number of children receiving Somatropin, although the relationship is uncertain.
Approximately 2% of patients develop antibodies. Of the 232 patients receiving somatropin for >6 months, 4.7% had serum binding of radiolabeled growth hormone in excess of twice the binding observed in control sera.
Somatropin may cause headaches,localized muscle pain,arthralgia,carpal tunnel syndrome, weakness,?mild hyperglycemia, and glucx)suria Mild transient edema occurs in 2.5% of patients early during treatment Local urticarial reactions have rarely?been reported at the injection site.
(hyperglycemia)and lipolysis within?2-4 hours. Large doses of growth hormone may impair glucose?tolerance ana induce insulin?resistance.The exact mechanism is not known.Children with hypopituitarism sometimes experience fasting hypoglycemia that is improved by somatropin therapy.
Children who are not growth hormone-deficient somatropin may provoke hyperinsulinemia without impairment of glucose tolerance.
It is not known whether somatropin is excreted in breast milk. Exercise caution when administering to nursing mother.